Ocjena Aktivnosti Ankilozantnog Spondilitisa Primjenom Basdai I Asdas Instrumenta Scoring of Disease Activity Using Basdai and Asdas Method in Ankylosing Spondylitis
نویسندگان
چکیده
Za procjenu aktivnosti ankilozantnog spondilitisa (AS) najčešće se koristi Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) kojim se kroz 6 pitanja evaluira 5 osnovnih simptoma bolesti (umor, bol u kralježnici, bol i oteklina zglobova, osjetljivost enteza, intenzitet i trajanje jutarnje zakočenosti). Za razliku od navedenog, Ankylosing Spondylitis Disease Activity Score (ASDAS) je indeks za procjenu aktivnosti AS koji uz bolesnikovu procjenu simptoma bolesti (bolova u kralježnici, trajanja jutarnje zakočenosti, aktivnosti bolesti, bolova i otekline perifernih zglobova) uključuje reaktante akutne faze (SE ili CRP). Cilj rada bio je usporediti BASDAI i ASDAS indekse na skupini bolesnika s AS, procijeniti njihovu sukladnost i utjecaj SE, umora i boli u kralježnici na dobivene vrijednosti. Istraživanje je provedeno po tipu presječne studije u skupini od 36 bolesnika s AS kojima je procijenjena razina aktivnosti bolesti BASDAI i ASDAS (SE) indeksom. Statistička analiza podataka učinjena je Student t-testom te tablicama frekvencije za neparametrijske podatke. Kao što je i očekivano potvrđena je značajna korelacija između BASDAI i ASDAS indeksa (r=0,796; p=0,00). Prosječna vrijednost BASDAI/ASDAS svih bolesnika iznosila je 4,2/2,8. Od 36 bolesnika s AS prema BASDAI indeksu 42% je imalo blago aktivnu bolest (BASDAI <4), dok je prema ASDAS indeksu 44% bolesnika imalo jako aktivnu bolest (ASDAS 2,1-3,5). Bolesnici s višim BASDAI indeksom imaju statistički značajno izraženiji umor i bol u kralježnici bez statistički značajne razlike u sedimentaciji (p=0,120). Ispitanici s višim ASDAS indeksom imaju također značajno izraženiji umor i bol u kralježnici, ali za razliku od BASDAI-a i sedimentaciju (p=0,001). ASDAS je noviji klinički indikator aktivnosti AS koji je usporediv s BASDAI instrumentom. U ovoj skupini bolesnika ASDAS se čini osjetljivijim upitnikom jer diskriminira više bolesnika s aktivnom bolešću.
منابع مشابه
[Scoring of disease activity using BASDAI and ASDAS method in ankylosing spondylitis].
Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) is the most frequently used ankylosing spondylitis activity assesment by which through 6 questions 5 basic diseases symptoms (fatigue, back pain, joint pain/swelling, enthesitic points, intensity and duration of morning stiffness) are being evaluated. In distinction from mentioned, Ankylosing Spondylitis Disease Activity Score (ASDAS) ...
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